2016年9月22日星期四

The oldest (89 year-old) pancreatic cancer patient’s Nanoknife surgery was completed at FUDA

In the morning of September 13, China News Service, Nanfang Daily, Yangcheng Evening News, Southern Metropolis Daily and New Express etc. media reporters gathered at Guangzhou Fuda Cancer Hospital for reporting the recent first case of an 89-year old pancreatic cancer patient’s Nanoknife surgery in the world. It’s the oldest patient around the world that accepted Nanoknife surgery. The success of this operation marks the great progress and breakthrough in Nanoknife therapy for pancreatic cancer.

It’s learned that pancreatic cancer is the most malignant tumor of digestive system. And its morbidity is on the rise. In 2010, about 36.8 thousand people died of pancreatic cancer. Pancreatic cancer is the fourth most common cancer cause of cancer-related death in America. Its peak incidence age is between 70 to 90 years old. The incidence rate of male and female is about same.
 
At the same time, it’s a dangerous disease. Because it located in hidden position and the early symptoms are not apparent. Most patients find it in terminal stage. Less than 20% of patient can accept operation, and more than 80% of patient can’t accept it.
Now, as for pancreatic cancer, most adopt chemotherapy, but the effect is poor. The median survival time of advanced local pancreatic cancer is only 6 months. If occur metastasis, the average survival time is only 3 months. With highest death rate, pancreatic cancer is called “The king of cancer”.
However, with Nanoknife technique, prognosis of pancreatic cancer patient has been improved. Its advantage is can insert several needle electrodes to the tumor that can’t be removed by operation. It can kill cancerous cells by electrodes without damaging bile duct, pancreatic duct, vascular and intestine etc. such normal tissues apparently.

Data from research of America shows that applying NanoKnife therapy to treat advanced pancreatic cancer doubles the survival time on average. Guangzhou Fuda Cancer Hospital has introduced this technique and applied in clinic research since 2014. It’s the first hospital introduced NanoKnife therapy and the hospital with most cases of applying NanoKnife therapy in treatment in mainland of China.

On August this year, Fuda Cancer Hospital treated an 89-year old pancreatic cancer patient from Philippines. He accepted Nanoknife therapy and the surgery was very successful. Investigation shows that the patient is the oldest patient who had Nanoknife therapy for pancreatic cancer in the world at present. The success of the surgery sets a new record in the field of medicine.
 


The patient was born in 1927. On March this year, he developed yellow skin and yellow sclera with symptoms of itching, dark urine and bad appetite etc. After having physical examination at local hospital, he was diagnosed as pancreatic cancer. On Aril this year, he had operation at local hospital. Doctor found the tumor couldn’t be cut during operation. Then, they closed the abdomen after chole enterostomy. Then the patient became worse. He lost about 4 kilogram over three months, and the pain became worse.
On August 7, he went to Guangzhou Fuda Cancer Hospital. In the morning of August 11, chief president of Fuda Cancer Hospital Xu Kecheng organized experts to have a consultation to make treatment plan. Dr. Niu Lizhi was the surgeon performing Nanoknife surgery. After operation, the pain was relieved and his condition became better. He could get off bed on the second day after surgery. After a week, his examination shown that CAI99 (tumor marker) index dropped significantly. The effect of the surgery was remarkable. 

Dr. Niu Lizhi explained, patient had cardio-cerebral vascular disease with history of diabetes and hypertension etc, and his vessel is fragile, therefore, it’s easy to cause mass blooding during puncturing. Besides, patient’s gastrointestinal function was weak and the bile duct was surrounded by the tumor, which would cause intestine damage, biliary fistula and pancreatic fistula etc. The risk and difficulty of the surgery is so great unprecedentedly.
“Before surgery, expert teams made a detailed treatment plan through, especially in designing the puncturing route in operation thoroughly. Guided by the advanced equipment and GPRS, needles of NanoKnife (irreversible electroporation) were placed in targeted position to kill cancerous cells.”Niu Lizhi told the author.


Besides making detailed treatment plan in advance, medical team’s perfect cooperation was also important. Dr. Niu Lizhi said: “Experts of ultrasound department, CT department and cardiology department gave overall technical supports in the surgery for completing the world-class highly difficult surgery.”The surgery’s success proves the safety and validity of this technique. At the same time, it also shows that Nanoknife therapy in China has reached the world level.



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